dCubilin- or dAMN-mediated protein reabsorption in Drosophila nephrocytes modulates longevity

• Main Authors: Xiaoming Feng (Author), Xizhen Hong (Author), Qiuxia Fan (Author), Liting Chen (Author), Jing Li (Author), Juan Deng (Author), Siqiao Gong (Author), Fan Fan Hou (Author), Fujian Zhang (Author)
• Format: Book
• Published: The Company of Biologists, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aging is a multifaceted process regulated by multiple cellular pathways, including the proteostasis network. Pharmacological or genetic enhancement of the intracellular proteostasis network extends lifespan and prevents age-related diseases. However, how proteostasis is regulated in different tissue...