MiR-146a G/C rs2910164 variation in South African Indian and Caucasian patients with psoriatic arthritis

• Main Authors: Ajesh B. Maharaj (Author), Pragalathan Naidoo (Author), Terisha Ghazi (Author), Naeem S. Abdul (Author), Shanel Dhani (Author), Taskeen F. Docrat (Author), Prithiksha Ramkaran (Author), Paul-Peter Tak (Author), Niek de Vries (Author), Anil A. Chuturgoon (Author)
• Formato: Livro
• Publicado em: BMC, 2018-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Psoriasis and psoriatic arthritis (PsA) are inflammatory associated autoimmune disorders. MicroRNA (miR)-146a plays a crucial role in regulating inflammation. A single nucleotide polymorphism in the miR-146a gene (rs2910164), aberrantly alters its gene expression and linked with...