Circulating tumor cell clusters-associated gene plakoglobin is a significant prognostic predictor in patients with breast cancer

• Main Authors: Wataru Goto (Author), Shinichiro Kashiwagi (Author), Yuka Asano (Author), Koji Takada (Author), Katsuyuki Takahashi (Author), Takaharu Hatano (Author), Tsutomu Takashima (Author), Shuhei Tomita (Author), Hisashi Motomura (Author), Masahiko Ohsawa (Author), Kosei Hirakawa (Author), Masaichi Ohira (Author)
• Format: Book
• Published: BMC, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Circulating tumor cells (CTCs) are linked to metastatic relapse and are regarded as a prognostic marker for human cancer. High expression of plakoglobin, a cell adhesion protein, within the primary tumor is positively associated with CTC clusters in breast cancer. In this study,...