Phloretamide Protects against Diabetic Kidney Damage and Dysfunction in Diabetic Rats by Attenuating Hyperglycemia and Hyperlipidemia, Suppressing NF-κβ, and Upregulating Nrf2

Phloretamide Protects against Diabetic Kidney Damage and Dysfunction in Diabetic Rats by Attenuating Hyperglycemia and Hyperlipidemia, Suppressing NF-κβ, and Upregulating Nrf2

Potent hypoglycemic and antioxidant effects were recently reported for the apple-derived phenolic compound phloretamide (PLTM). The renoprotective effects of this compound are yet to be shown. This study aimed to examine the potential of PLTM to prevent diabetic nephropathy in streptozotocin-induced...

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Main Authors: Rasha Al-Hussan (Author), Nawal A. Albadr (Author), Ghedeir M. Alshammari (Author), Soheir A. Almasri (Author), Farah Fayez Alfayez (Author), Mohammed Abdo Yahya (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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