The Novel Alpha-2 Adrenoceptor Inhibitor Beditin Reduces Cytotoxicity and Huntingtin Aggregates in Cell Models of Huntington's Disease

• Asıl Yazarlar: Elisabeth Singer (Yazar), Lilit Hunanyan (Yazar), Magda M. Melkonyan (Yazar), Jonasz J. Weber (Yazar), Lusine Danielyan (Yazar), Huu Phuc Nguyen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Huntington's disease (HD) is a monogenetic neurodegenerative disorder characterized by the accumulation of polyglutamine-expanded huntingtin (mHTT). There is currently no cure, and therefore disease-slowing remedies are sought to alleviate symptoms of the multifaceted disorder. Encouraging find...