Synthesis, Docking and Acetylcholinesterase Inhibitory Evaluation of 1,3,4-Thiadiazole Derivatives as Potential Anti-Alzheimer Agents

• Main Authors: Ahmad Mohammadi-Farani (Author), Milad Takesh (Author), Mahsa Mohammadi (Author), Amin Hosseini (Author), Amin Aliabadi (Author), Alireza Aliabadi (Author)
• פורמט: ספר
• יצא לאור: Tabriz University of Medical Sciences, 2024-07-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Background: According to the cholinergic hypothesis for Alzheimer's disease, potentiation of cholinergic neurotransmission is one of the best strategies for combating dementia. Methods: A new series of benzamide derivatives bearing 1,3,4-thiadiazole nucleus were synthesized and subsequently, th...