Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies

Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies

Amorphous formulation technologies to improve oral absorption of poorly soluble active pharmaceutical ingredients (APIs) have become increasingly prevalent. Currently, polymer-based amorphous formulations manufactured by spray drying, hot melt extrusion (HME), or co-precipitation are most common. Ho...

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Main Authors: Felix Ditzinger (Author), Daniel J. Price (Author), Anita Nair (Author), Johanna Becker-Baldus (Author), Clemens Glaubitz (Author), Jennifer B. Dressman (Author), Christoph Saal (Author), Martin Kuentz (Author)
Format: Book
Published: MDPI AG, 2019-11-01T00:00:00Z.
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