A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the <it>ret</it> proto-oncogene related to MEN 2A.

• Үндсэн зохиолчид: Godoy Clara (Зохиогч), Perinetti Héctor (Зохиогч), Pusiol Eduardo (Зохиогч), Roqué María (Зохиогч), Mayorga Luis S (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2002-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Multiple endocrine neoplasias type 2A (MEN 2A) is a dominantly inherited cancer syndrome. Missence mutations in the codon encoding cysteine 634 of the <it>ret</it> proto-oncogene have been found in 85% of the MEN 2A famil...