Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse

• Main Authors: Fiorentina Roviezzo (Author), Antonietta Rossi (Author), Elisabetta Caiazzo (Author), Pierangelo Orlando (Author), Maria A. Riemma (Author), Valentina M. Iacono (Author), Andrea Guarino (Author), Armando Ialenti (Author), Carla Cicala (Author), Alessio Peritore (Author), Raffaele Capasso (Author), Vincenzo Di Marzo (Author), Angelo A. Izzo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One important risk factor for the development of asthma is allergen sensitization. Recent increasing evidence suggests a prominent role of mast cells in asthma pathophysiology. Since Palmitoylethanolamide (PEA), an endogenous lipid mediator chemically related to - and co-released with- the endocanna...