Benzoylphenyl thiocyanates are new, effective inhibitors of the mycobacterial resuscitation promoting factor B protein

• Main Authors: Galina R. Demina (Author), Vadim D. Nikitushkin (Author), Margarita O. Shleeva (Author), Olga B. Riabova (Author), Alexander Yu. Lepioshkin (Author), Vadim A. Makarov (Author), Arseny S. Kaprelyants (Author)
• Format: Book
• Published: BMC, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Resuscitation promoting factors (Rpfs) are the proteins involved in the process of reactivation of the dormant cells of mycobacteria. Recently a new class of nitrophenylthiocyanates (NPTs), capable of inhibiting the biological and enzymatic activities of Rpfs has been discovered....