Synthesis and antinociceptive activity of novel mannich base derivatives of some new fused 3,5-pyrazolidinedione

• Main Authors: Abhishek Tiwari (Author), Anita Singh (Author)
• 格式: 图书
• 出版: Wolters Kluwer Medknow Publications, 2014-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

In the present study, a novel series of mannich bases 1-((1-substituted ethyl-1H-benzo[d] imidazol-2-yl) methyl)-2-substituted phenylpyrazolidine-3,5-dione 3(a-l) were synthesized and evaluated as antinociceptive agents in mice by Eddy's hot plate and acetic acid-induced writhing models. The st...