Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia

• Hoofdauteurs: Claudio Nardiello (Auteur), Ivana Mižíková (Auteur), Diogo M. Silva (Auteur), Jordi Ruiz-Camp (Auteur), Konstantin Mayer (Auteur), István Vadász (Auteur), Susanne Herold (Auteur), Werner Seeger (Auteur), Rory E. Morty (Auteur)
• Formaat: Boek
• Gepubliceerd in: The Company of Biologists, 2017-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Progress in developing new therapies for bronchopulmonary dysplasia (BPD) is sometimes complicated by the lack of a standardised animal model. Our objective was to develop a robust hyperoxia-based mouse model of BPD that recapitulated the pathological perturbations to lung structure noted in infants...