Comparison of fully-automated radiosyntheses of [11C]erlotinib for preclinical and clinical use starting from in target produced [11C]CO2 or [11C]CH4

Comparison of fully-automated radiosyntheses of [11C]erlotinib for preclinical and clinical use starting from in target produced [11C]CO2 or [11C]CH4

Abstract Background [11C]erlotinib has been proposed as a PET tracer to visualize the mutational status of the epidermal growth factor receptor (EGFR) in cancer patients. For clinical use, a stable, reproducible and high-yielding radiosynthesis method is a prerequisite. In this work, two production...

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Main Authors: Cécile Philippe (Author), Severin Mairinger (Author), Verena Pichler (Author), Johann Stanek (Author), Lukas Nics (Author), Markus Mitterhauser (Author), Marcus Hacker (Author), Thomas Wanek (Author), Oliver Langer (Author), Wolfgang Wadsak (Author)
Format: Book
Published: SpringerOpen, 2018-05-01T00:00:00Z.
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3rd Floor Main Library

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