Cellular cholesterol distribution influences proteolytic release of the LRP-1 ectodomain

• Autori principali: Bassil eDEKKY (Autore), Amandine eWAHART (Autore), Hervé eSARTELET (Autore), Michael eFERE (Autore), Jean-François eANGIBOUST (Autore), Stéphane eDEDIEU (Autore), Olivier ePIOT (Autore), Jérôme eDEVY (Autore), Hervé eEMONARD (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2016-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Low-Density Lipoprotein Receptor-related Protein-1 (LRP-1) is a multifunctional matricellular receptor composed of a large ligand-binding subunit (515-kDa α-chain) associated with a short trans-membrane subunit (85-kDa β-chain). LRP-1, which exhibits both endocytosis and cell signaling properties, p...