Cellular cholesterol distribution influences proteolytic release of the LRP-1 ectodomain

• Main Authors: Bassil eDEKKY (Author), Amandine eWAHART (Author), Hervé eSARTELET (Author), Michael eFERE (Author), Jean-François eANGIBOUST (Author), Stéphane eDEDIEU (Author), Olivier ePIOT (Author), Jérôme eDEVY (Author), Hervé eEMONARD (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Low-Density Lipoprotein Receptor-related Protein-1 (LRP-1) is a multifunctional matricellular receptor composed of a large ligand-binding subunit (515-kDa α-chain) associated with a short trans-membrane subunit (85-kDa β-chain). LRP-1, which exhibits both endocytosis and cell signaling properties, p...