Implications of genetic variability of Trypanosoma cruzi for the pathogenesis of Chagas disease Implicações da variabilidade genética do Trypanosoma cruzi na patogênese da doença de Chagas

• Main Authors: Fernanda da Silva Manoel-Caetano (Author), Ana Elizabete Silva (Author)
• Format: Book
• Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz, 2007-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi, the etiological agent of Chagas disease, presents a high degree of intraspecific genetic variability, with possible implications for the clinical forms of the disease, like the development of cardiopathy, megaesophagus, and megacolon, alone or in combination. This tissue tropism i...