Antihypertensive effects of pentacyclic triterpenoid from Convolvulus pluricaulis and its plausible mechanism of action hypothesizing its selectivity targeting Mineralocorticoid receptor of RAAS.

• Main Authors: Kanagasabai Somarathinam (Author), Seshan Gunalan (Author), Ananthasri Sailapathi (Author), Dharani Amirtha Metilda A (Author), Balashanmugam Pannerselvam (Author), M. Mohanasundari (Author), Ashok Kumar Balaraman (Author), Gugan Kothandan (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The renin-angiotensin-aldosterone system (RAAS) is important in maintaining blood pressure and malfunction of this system leads to the main cause of hypertension. Though a variety of synthetic inhibitors have been used to treat hypertension and related disorders, chronic use of these inh...