Mechanisms and therapeutic targets of ferroptosis: Implications for nanomedicine design

• Main Authors: Meihong Zhang (Author), Mengqin Guo (Author), Yue Gao (Author), Chuanbin Wu (Author), Xin Pan (Author), Zhengwei Huang (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is a nonapoptotic form of cell death and differs considerably from the well-known forms of cell death in terms of cell morphology, genetics, and biochemistry. The three primary pathways for cell ferroptosis are system Xc−/glutathione peroxidase 4 (GPX4), lipid metabolism, and ferric meta...