EphB4 inhibitor overcome the acquired resistance to cisplatin in melanomas xenograft model

• Main Authors: Xiaokun Yang (Author), Yadong Yang (Author), Shuqian Tang (Author), Hui Tang (Author), Guihong Yang (Author), Qiaoyu Xu (Author), Jinjin Wu (Author)
• Format: Book
• Published: Elsevier, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this paper is to investigate the possible mechanisms of resistance to chemotherapy in melanoma from the perspective of molecular biology and to discuss the strategies to overcome them. Cisplatin, a DNA-damaging compound that triggers apoptotic cell death, is commonly used in the treat...