Emodin ameliorates renal injury and fibrosis via regulating the miR-490-3p/HMGA2 axis

• Main Authors: Liulin Wang (Author), Xuerui Wang (Author), Gang Li (Author), Shanshan Zhou (Author), Rui Wang (Author), Qi Long (Author), Min Wang (Author), Liang Li (Author), Hai Huang (Author), Yuanming Ba (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal fibrosis is a major pathological feature of chronic kidney disease (CKD). While emodin is reported to elicit anti-fibrotic effects on renal injury, little is known about its effects on microRNA (miRNA)-modulated mechanisms in renal fibrosis. In this study, we established a unilateral ureteral...