Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption

• Main Authors: Olena Mackert (Author), Eva Katrin Wirth (Author), Rongwan Sun (Author), Jennifer Winkler (Author), Aoxue Liu (Author), Kostja Renko (Author), Séverine Kunz (Author), Joachim Spranger (Author), Sebastian Brachs (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Alterations in mitochondrial function play an important role in the development of various diseases, such as obesity, insulin resistance, steatohepatitis, atherosclerosis and cancer. However, accurate assessment of mitochondrial respiration ex vivo is limited and remains highly challengin...