Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis

• Main Authors: Jiahui Ni (Author), Lijie Zhang (Author), Guize Feng (Author), Weilian Bao (Author), Yirui Wang (Author), Yuran Huang (Author), Tongqing Chen (Author), Jieli Chen (Author), Xinyue Cao (Author), Keyuan You (Author), Sheng Tan (Author), Thomas Efferth (Author), Hong Li (Author), Bo Li (Author), Xiaoyan Shen (Author), Yan You (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The damage of integrated epithelial epithelium is a key pathogenic factor and closely associated with the recurrence of ulcerative colitis (UC). Here, we reported that vanillic acid (VA) exerted potent therapeutic effects on DSS-induced colitis by restoring intestinal epithelium homeostasis via the...