Mathematical Modeling Reveals the Role of Hypoxia in the Promotion of Human Mesenchymal Stem Cell Long-Term Expansion

Many experimental studies have found that human mesenchymal stem cells (MSCs) in long-term culture exhibited enhanced cell proliferation and prolonged lifespan under hypoxia (around 1%-7% oxygen) against the normoxic condition (about 21% oxygen). Inspired by the experimental findings, we aimed to in...

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Päätekijät: Shuhua Gao (Tekijä), Cheng Xiang (Tekijä), Kairong Qin (Tekijä), Changkai Sun (Tekijä)
Aineistotyyppi: Kirja
Julkaistu: Hindawi Limited, 2018-01-01T00:00:00Z.
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