Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming

• Main Authors: Emmanouela Tsagkaraki (Author), Adilson Guilherme (Author), Sarah M. Nicoloro (Author), Mark Kelly (Author), Lawrence M. Lifshitz (Author), Hui Wang (Author), Kyounghee Min (Author), Leslie A. Rowland (Author), Kaltinaitis B. Santos (Author), Nicole Wetoska (Author), Randall H. Friedline (Author), Stacy A. Maitland (Author), Min Chen (Author), Lee S. Weinstein (Author), Scot A. Wolfe (Author), Jason K. Kim (Author), Michael P. Czech (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Nuclear receptor interacting protein 1 (NRIP1) suppresses energy expenditure via repression of nuclear receptors, and its depletion markedly elevates uncoupled respiration in mouse and human adipocytes. We tested whether NRIP1 deficient adipocytes implanted into obese mice would enhance...