Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming

• Autors principals: Emmanouela Tsagkaraki (Autor), Adilson Guilherme (Autor), Sarah M. Nicoloro (Autor), Mark Kelly (Autor), Lawrence M. Lifshitz (Autor), Hui Wang (Autor), Kyounghee Min (Autor), Leslie A. Rowland (Autor), Kaltinaitis B. Santos (Autor), Nicole Wetoska (Autor), Randall H. Friedline (Autor), Stacy A. Maitland (Autor), Min Chen (Autor), Lee S. Weinstein (Autor), Scot A. Wolfe (Autor), Jason K. Kim (Autor), Michael P. Czech (Autor)
• Format: Llibre
• Publicat: Elsevier, 2023-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objectives: Nuclear receptor interacting protein 1 (NRIP1) suppresses energy expenditure via repression of nuclear receptors, and its depletion markedly elevates uncoupled respiration in mouse and human adipocytes. We tested whether NRIP1 deficient adipocytes implanted into obese mice would enhance...