Severe Combined Dyslipidemia With a Complex Genetic Basis

• Hoofdauteurs: Ryan Le MD (Auteur), Minan Abbas MB ChB, FRCPC (Auteur), Adam D. McIntyre BSc (Auteur), Robert A. Hegele MD, FRCPC, FACP (Auteur)
• Formaat: Boek
• Gepubliceerd in: SAGE Publishing, 2019-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background. Familial dysbetalipoproteinemia (also known as type 3 hyperlipoproteinemia) is typically associated with homozygosity for the apolipoprotein E2 isoform, but also sometimes with dominant rare missense variants in the APOE gene. Patients present with roughly equimolar elevations of cholest...