Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways

• Main Authors: Valentina Caputi (Author), Ilaria Marsilio (Author), Silvia Cerantola (Author), Mona Roozfarakh (Author), Isabella Lante (Author), Francesca Galuppini (Author), Massimo Rugge (Author), Eleonora Napoli (Author), Cecilia Giulivi (Author), Genny Orso (Author), Maria Cecilia Giron (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Toll-like receptors (TLRs) play a pivotal role in the homeostatic microflora-host crosstalk. TLR4-mediated modulation of both motility and enteric neuronal survival has been reported mainly for colon with limited information on the role of TLR4 in tuning structural and functional integrit...