Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin.

• Main Authors: Dorothy Yeboah-Manu (Author), Grace S Kpeli (Author), Marie-Thérèse Ruf (Author), Kobina Asan-Ampah (Author), Kwabena Quenin-Fosu (Author), Evelyn Owusu-Mireku (Author), Albert Paintsil (Author), Isaac Lamptey (Author), Benjamin Anku (Author), Cynthia Kwakye-Maclean (Author), Mercy Newman (Author), Gerd Pluschke (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Buruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli. Surrounding tissue is destroyed by the cytotoxic macrolide toxin mycolactone produced by mic...