Nrf2 Regulates Anti-Inflammatory <i>A20</i> Deubiquitinase Induction by LPS in Macrophages in Contextual Manner

• Hauptverfasser: Haranatha R. Potteti (Verfasst von), Lalith K. Venkareddy (Verfasst von), Patrick M. Noone (Verfasst von), Aparna Ankireddy (Verfasst von), Chandramohan R. Tamatam (Verfasst von), Dolly Mehta (Verfasst von), Chinnaswamy Tiruppathi (Verfasst von), Sekhar P. Reddy (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2021-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The aberrant regulation of inflammatory gene transcription following oxidant and inflammatory stimuli can culminate in unchecked systemic inflammation leading to organ dysfunction. The Nrf2 transcription factor dampens cellular stress and controls inflammation by upregulating antioxidant gene expres...