The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto's Thyroiditis

• Main Authors: Stana Tokić (Author), Mario Štefanić (Author), Ljubica Glavaš-Obrovac (Author), Sonja Jaman (Author), Eva Novosadová (Author), Jana Petrkova (Author), Zdenka Navratilova (Author), Mirjana Suver Stević (Author), Martin Petrek (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hashimoto's thyroiditis (HT) is an organ-specific autoimmune disorder characterized by progressive thyroid failure. Th1 and Treg subset of CD4+ cells have been implicated in the pathogenesis; however, less is known about their respective roles across the spectrum of HT clinical presentations. T...