Identification of Endogenous Surrogate Ligands for Human P2Y Receptors Through an In Silico Search
G protein-coupled receptors (GPCRs) are distributed widely throughout the human body, and nearly 50% of current medicines act on a GPCR. GPCRs are considered to consist of seven transmembrane α-helices that form an α-helical bundle in which agonists and antagonists bind. A 3D structure of the target...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2004-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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