Transcriptome analysis of peripheral blood of Schistosoma mansoni infected children from the Albert Nile region in Uganda reveals genes implicated in fibrosis pathology.

• Main Authors: Joyce Namulondo (Author), Oscar Asanya Nyangiri (Author), Magambo Phillip Kimuda (Author), Peter Nambala (Author), Jacent Nassuuna (Author), Moses Egesa (Author), Barbara Nerima (Author), Savino Biryomumaisho (Author), Claire Mack Mugasa (Author), Immaculate Nabukenya (Author), Drago Kato (Author), Alison Elliott (Author), Harry Noyes (Author), Robert Tweyongyere (Author), Enock Matovu (Author), Julius Mulindwa (Author), TrypanoGEN+ research group of the H3Africa consortium (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over 290 million people are infected by schistosomes worldwide. Schistosomiasis control efforts focus on mass drug treatment with praziquantel (PZQ), a drug that kills the adult worm of all Schistosoma species. Nonetheless, re-infections have continued to be detected in endemic areas with individual...