Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

• Үндсэн зохиолчид: Qiao Liu (Зохиогч), Martina Sundqvist (Зохиогч), Wenyan Li (Зохиогч), André Holdfeldt (Зохиогч), Liang Zhang (Зохиогч), Lena Björkman (Зохиогч), Johan Bylund (Зохиогч), Claes Dahlgren (Зохиогч), Cai Wang (Зохиогч), Xiaodong Zhao (Зохиогч), Huamei Forsman (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2019-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Neutrophils and eosinophils are multifunctional granulocytes derived from common myelocytic-committed progenitor cells. Severe congenital neutropenia 1 (SCN1) caused by ELANE mutations is a rare disease characterized by very low numbers of circulating neutrophils. Little is known...