Characterization of organic anion transporting polypeptide 1b2 knockout rats generated by CRISPR/Cas9: a novel model for drug transport and hyperbilirubinemia disease

Organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1/3) as important uptake transporters play a fundamental role in the transportation of exogenous drugs and endogenous substances into cells. Rat OATP1B2, encoded by the Slco1b2 gene, is homologous to human OATP1B1/3. Although OATP1B1/3 is ver...

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Main Authors: Xinrun Ma (Author), Xuyang Shang (Author), Xuan Qin (Author), Jian Lu (Author), Mingyao Liu (Author), Xin Wang (Author)
Format: Book
Published: Elsevier, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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