MicroRNA let-7i Inhibits Histone Lysine Demethylase KDM5B to Halt Esophageal Cancer Progression

• Main Authors: Yang Yang (Author), Wenhua Li (Author), Bochong Wei (Author), Kai Wu (Author), Donglei Liu (Author), Dengyan Zhu (Author), Chunyang Zhang (Author), Fengbiao Wen (Author), Yuxia Fan (Author), Song Zhao (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies have suggested that microRNA let-7i is a tumor suppressor in human cancers, including esophageal cancer, but its underlying mechanism is not yet fully understood. We investigated the role and mechanisms of let-7i in the progression of esophageal cancer. We first showed that let-7i was...