Synthesis and evaluation of AKR1C inhibitory properties of A-ring halogenated oestrone derivatives

Enzymes AKR1C regulate the action of oestrogens, androgens, and progesterone at the pre-receptor level and are also associated with chemo-resistance. The activities of these oestrone halides were investigated on recombinant AKR1C enzymes. The oestrone halides with halogen atoms at both C-2 and C-4 p...

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Main Authors: Maša Sinreih (Author), Rebeka Jójárt (Author), Zoltán Kele (Author), Tomaž Büdefeld (Author), Gábor Paragi (Author), Erzsébet Mernyák (Author), Tea Lanišnik Rižner (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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