Synthesis and evaluation of AKR1C inhibitory properties of A-ring halogenated oestrone derivatives
Enzymes AKR1C regulate the action of oestrogens, androgens, and progesterone at the pre-receptor level and are also associated with chemo-resistance. The activities of these oestrone halides were investigated on recombinant AKR1C enzymes. The oestrone halides with halogen atoms at both C-2 and C-4 p...
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Main Authors: | , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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A1234.567 |
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