Resveratrol improves osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation

• Egile Nagusiak: Ting Zhou (Egilea), Yurong Yan (Egilea), Chenchen Zhao (Egilea), Yao Xu (Egilea), Qiong Wang (Egilea), Na Xu (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Resveratrol has been confirmed to improve bone quality and delay osteoporosis, but the mechanisms have not been thoroughly elucidated. In this report, we investigated the osteogenic differentiation effect of resveratrol on senescent bone mesenchymal stem cells (BMSCs) and the involvement...