Schistosoma japonicum egg specific protein SjE16.7 recruits neutrophils and induces inflammatory hepatic granuloma initiation.

• Main Authors: Chenyun Wu (Author), Qing Chen (Author), Yan Fang (Author), Jianhua Wu (Author), Yanyan Han (Author), Ying Wang (Author), Yang Yang (Author), Min Chu (Author), Yan Feng (Author), Linping Tan (Author), Xiaokui Guo (Author), Wei Hu (Author), Zhaojun Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neutrophils are known to play a major role in the egg granulomatous lesions caused by Schistosoma japonicum, but the precise mechanism by which eggs recruit or active neutrophil is unknown. Here we report S. japonicum egg specific EF-hand protein-SjE16.7 is a potent neutrophil recruiter and initiate...