Comparative untargeted proteomic analysis of ADME proteins and tumor antigens for tumor cell lines

• Main Authors: Xiaomei Gu (Author), Qing Xiao (Author), Qian Ruan (Author), Yuezhong Shu (Author), Ashok Dongre (Author), Ramaswamy Iyer (Author), W. Griffith Humphreys (Author), Yurong Lai (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, total membrane proteins from tumor cell lines including HepG2, Hep3B2, H226, Ovcar3 and N87 were extracted and digested with γLysC and trypsin. The resulting peptide lysate were pre-fractionated and subjected to untargeted quantitative proteomics analysis using a high resolutio...