The 4-Hydroxynonenal-Protein Adducts and Their Biological Relevance: Are Some Proteins Preferred Targets?

• Prif Awduron: Lidija Milkovic (Awdur), Neven Zarkovic (Awdur), Zlatko Marusic (Awdur), Kamelija Zarkovic (Awdur), Morana Jaganjac (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2023-04-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

It is well known that oxidative stress and lipid peroxidation (LPO) play a role in physiology and pathology. The most studied LPO product with pleiotropic capabilities is 4-hydroxynonenal (4-HNE). It is considered as an important mediator of cellular signaling processes and a second messenger of rea...