Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute Scrub Typhus infection.

• Hauptverfasser: Daniel H Paris (Verfasst von), Stuart D Blacksell (Verfasst von), Pruksa Nawtaisong (Verfasst von), Kemajittra Jenjaroen (Verfasst von), Achara Teeraratkul (Verfasst von), Wirongrong Chierakul (Verfasst von), Vanaporn Wuthiekanun (Verfasst von), Pacharee Kantipong (Verfasst von), Nicholas P J Day (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

There is an urgent need to develop rapid and accurate point-of-care (POC) technologies for acute scrub typhus diagnosis in low-resource, primary health care settings to guide clinical therapy.In this study we present the clinical evaluation of loop-mediated isothermal PCR assay (LAMP) in the context...