5-Benzyliden-2-(5-methylthiazol-2-ylimino)thiazolidin-4-ones as Antimicrobial Agents. Design, Synthesis, Biological Evaluation and Molecular Docking Studies

• Main Authors: Michelyne Haroun (Author), Christophe Tratrat (Author), Aggeliki Kolokotroni (Author), Anthi Petrou (Author), Athina Geronikaki (Author), Marija Ivanov (Author), Marina Kostic (Author), Marina Sokovic (Author), Alejandro Carazo (Author), Přemysl Mladěnka (Author), Nagaraja Sreeharsha (Author), Katharigatta N. Venugopala (Author), Anroop B. Nair (Author), Heba S. Elsewedy (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we report the design, synthesis, computational and experimental evaluation of the antimicrobial activity, as well as docking studies of new 5-methylthiazole based thiazolidinones. All compounds demonstrated antibacterial efficacy, some of which (<b>1</b>, <b>4</b&...