Nintedanib Inhibits Wnt3a-Induced Myofibroblast Activation by Suppressing the Src/β-Catenin Pathway

• Main Authors: Xiaohe Li (Author), Xiaowei Liu (Author), Ruxia Deng (Author), Shaoyan Gao (Author), Haiyan Yu (Author), Kai Huang (Author), Qiuyan Jiang (Author), Rui Liu (Author), Xiaoping Li (Author), Liang Zhang (Author), Honggang Zhou (Author), Cheng Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by epithelial cell damage, myofibroblast activation, and collagen deposition. Multiple studies have documented that the Wnt/β-catenin pathway is aberrantly activated in IPF and plays a vital role in myofibroblast diffe...