Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling

• Main Authors: Ying Wang (Author), Zhi Wang (Author), Huiping Yang (Author), Shuze Chen (Author), Dekai Zheng (Author), Xiuying Liu (Author), Qinrui Jiang (Author), Ye Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intestinal fibrosis is considered to be a chronic complication of inflammatory bowel disease (IBD) and seriously threatening human health. Effective medical therapies or preventive measures are desirable but currently unavailable. Metformin has been proved to have a satisfactory anti-inflammatory ef...