Refining wet lab experiments with in silico searches: A rational quest for diagnostic peptides in visceral leishmaniasis.

• Main Authors: Bruno Cesar Bremer Hinckel (Author), Tegwen Marlais (Author), Stephanie Airs (Author), Tapan Bhattacharyya (Author), Hideo Imamura (Author), Jean-Claude Dujardin (Author), Sayda El-Safi (Author), Om Prakash Singh (Author), Shyam Sundar (Author), Andrew Keith Falconar (Author), Bjorn Andersson (Author), Sergey Litvinov (Author), Michael A Miles (Author), Pascal Mertens (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>The search for diagnostic biomarkers has been profiting from a growing number of high quality sequenced genomes and freely available bioinformatic tools. These can be combined with wet lab experiments for a rational search. Improved, point-of-care diagnostic tests for...