FKBP12 Depletion Leads to Loss of Sarcoplasmic Reticulum Ca2+ Stores in Rat Vas Deferens

• Main Authors: Christianne B.V. Scaramello (Author), Humberto Muzi-Filho (Author), Gisele Zapata-Sudo (Author), Roberto T. Sudo (Author), Valéria do M.N. Cunha (Author)
• 格式: 图书
• 出版: Elsevier, 2009-01-01T00:00:00Z.
• 主题: article
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The immunophilin 12-kDa FK506 binding protein (FKBP12) stabilizes intracellular Ca2+ release channel (CRC) activity in different tissues. In this work, the presence of FKBP12 in rat vas deferens (RVD) and its possible contribution to RVD function was investigated. Treatment under appropriate pH, tem...