Synthesis and Pharmacological Valorization of Derivatives of 4-Phenyl-1,5-Benzodiazepin-2-One

• Main Authors: Terence Nguema Ongone (Author), Redouane Achour (Author), Mostafa El Ghoul (Author), Latifa El Ouasif (Author), Khalid Taghzouti (Author), Meryem El Jemli (Author), Yahia Cherrah (Author), Katim Alaoui (Author), Amina Zellou (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of our work is to make a pharmacological study of molecules derived from 4-phenyl-1,5-benzodiazepin-2-one carrying long chains so that they have a structure similar to surfactants, with the benzodiazepine as a hydrophilic head and a carbon chain as a hydrophobic tail. First, we studied...