Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy

• Main Authors: Lei Tian (Author), Sheng Ding (Author), Yun You (Author), Tong-ruei Li (Author), Yan Liu (Author), Xiaohui Wu (Author), Ling Sun (Author), Tian Xu (Author)
• Format: Book
• Published: The Company of Biologists, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nemaline myopathy (NM) is one of the most common forms of congenital myopathy, and affects either fast myofibers, slow myofibers, or both. However, an animal model for congenital myopathy with fast-myofiber-specific atrophy is not available. Furthermore, mutations in the leiomodin-3 (LMOD3) gene hav...