Differential alternative splicing between hepatocellular carcinoma with normal and elevated serum alpha-fetoprotein

• Main Authors: Young-Joo Jin (Author), Habtamu Minassie Aycheh (Author), Seonggyun Han (Author), John Chamberlin (Author), Jaehang Shin (Author), Seyoun Byun (Author), Younghee Lee (Author)
• Format: Book
• Published: BMC, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Serum alpha-fetoprotein (AFP) is the approved serum marker for hepatocellular carcinoma (HCC) screening. However, not all HCC patients show high (≥ 20 ng/mL) serum AFP, and the molecular mechanisms of HCCs with normal (< 20 ng/mL) serum AFP remain to be elucidated. Therefore,...