Effect of β-cyclodextrin encapsulation on cytotoxic activity of acetylshikonin against HCT-116 and MDA-MB-231 cancer cell lines

• Main Authors: Milena D. Vukic (Author), Nenad L. Vukovic (Author), Suzana Lj. Popovic (Author), Danijela V. Todorovic (Author), Predrag M. Djurdjevic (Author), Sanja D. Matic (Author), Marina M. Mitrovic (Author), Ana M. Popovic (Author), Miroslava M. Kacaniova (Author), Dejan D. Baskic (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acetylshikonin (AcSh), as a red colored pigment found in roots of the plants from family Boraginaceae, showed excellent cytotoxic activity. Due to its hydrophobic nature, and thus poor bioavailability, the aim of this study was to prepare acetylshikonin/β-cyclodextrin (AcSh/β-CD) inclusion complex b...