Single-cell transcriptomic analysis reveals differential cell subpopulations and distinct phenotype transition in normal and dissected ascending aorta

• Автори: Yu-bin He (Автор), Hai-zhen Jin (Автор), Jin-long Zhao (Автор), Chong Wang (Автор), Wen-rui Ma (Автор), Jie Xing (Автор), Xiao-bin Zhang (Автор), Yang-yang Zhang (Автор), Huang-dong Dai (Автор), Nai-shi Zhao (Автор), Jian-feng Zhang (Автор), Guan-xin Zhang (Автор), Jing Zhang (Автор)
• Формат: Книга
• Опубліковано: BMC, 2022-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background Acute thoracic aortic dissection (ATAD) is a fatal condition characterized by tear of intima, formation of false lumen and rupture of aorta. However, the subpopulations of normal and dissected aorta remain less studied. Methods Single-cell RNA sequencing was performed including 5...