Development of Antibody-Oligonucleotide Complexes for Targeting Exosomal MicroRNA

• Главные авторы: Asako Yamayoshi (Автор), Shota Oyama (Автор), Yusuke Kishimoto (Автор), Ryo Konishi (Автор), Tsuyoshi Yamamoto (Автор), Akio Kobori (Автор), Hiroshi Harada (Автор), Eishi Ashihara (Автор), Hiroshi Sugiyama (Автор), Akira Murakami (Автор)
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• Опубликовано: MDPI AG, 2020-06-01T00:00:00Z.
• Предметы: article
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MicroRNAs in exosomes (exosomal miRNAs) are considered as significant targets for cancer therapy. Anti-miR oligonucleotides are often used for the functional inhibition of miRNAs; however, there are no studies regarding the regulation of exosomal miRNA functions. In this study, we attempted to devel...